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leprae. Anin silicostudy was done to know the molecular interactions in between DNA gyrase and WQ compounds. WQ-3334 and WQ-3810 were demonstrated to get higher inhibitory exercise againstM. lepraeDNA gyrase than Other folks. In addition, Assessment working with quinolone-resistantM. lepraeDNA gyrases showed that WQ-3334 had greater inhibitory acti